Certainly does explain your riding style, which obviously works with the miles you have under your belt !!!!!!sounds like a tried and well tested system and can make all the difference getting to and from your destination without a breakdown.
I also think its a good idea to have the right slide cut away and as large a pilot jet as possible as you have explained this is critical and can help coming of a lean part of the throttle range.
Needle settings really are a minefield for the average joe to set up so all I do is hope I,m in the ball park by bringing in a bit of choke on fast downhill runs just for a piece of mind.
My current experiment stage 4 200 iron is good for long runs and feedback,,,, at least if experiments go wrong there is know big loss........my 250 harry barlow is also iron lined as is the GT186 so like yourself not to keen on nicasil unless its a T5
PS what wheel rims and tyres do run on all these trips?